
TY  - JOUR
A1  - Chi, WO 
A1  - Hong, CL 
T1  - A Rapid Synthesis of 2,3,11,11a-Tetrahydro-6H-pyrazino[1,2-b]isoquinoline-1,4-diones Through an Amido Iminium Ion Cyclization
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1990
VL  - 43
IS  - 4
SP  - 773
EP  - 775
KW  - 
UR  - https://doi.org/10.1071/CH9900773 
N2  - 7,10-Dimethoxy-6-methyl-2,3,11,11a-tetrahydro-6H-pyrazino[1,2-b]isoquinoline-1,4-diones (5) and (6) were synthesized from glycine anhydride and 2,5-dimethoxybenzaldehyde through an amido iminium ion cyclization reaction. This method for the construction of the tetrahydroisoquinoline ring will be useful for the synthesis of saframycins. 
ER  -

