
TY  - JOUR
A1  - Evans, RF 
A1  - Savage, GP 
A1  - Gough, DA 
T1  - The Synthesis of 4(6)-t-Butylpyrimidines From 4(6)-Halopyrimidines by Using Higher-Order Lithium and Magnesium Organocuprate Reagents
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1990
VL  - 43
IS  - 4
SP  - 733
EP  - 740
KW  - 
UR  - https://doi.org/10.1071/CH9900733 
N2  - t-Butyllithium and t- butylmagnesium chloride cyanocuprates were used to prepare 4(6)-t- butylpyrimidines from the corresponding 4(6)-halopyrimidines . The highly hindered 2,4,5-tri-t-butyl-6-chloropyrimidine, containing an ortho-di-t-butyl arrangement, was prepared by this method. No alkyl group isomerization was observed but some substrate reduction was detected. 
ER  -

