
TY  - JOUR
A1  - Buckingham, DA 
A1  - Clark, CR 
A1  - Nangia, A 
T1  - The Acidity of Norfloxacin
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1990
VL  - 43
IS  - 2
SP  - 301
EP  - 309
KW  - 
UR  - https://doi.org/10.1071/CH9900301 
N2  - A 1H and 13C n.m.r. investigation of the fluoroquinolone carboxylic acid Norfloxacin (1) in D2O has allowed three pKa values to be determined, which correspond to carboxylic acid oxygen (pKaD 0.6), pyridone nitrogen (pKaD 6.9) and 'external' piperazine nitrogen (pKaD 9.25) ionization. 
ER  -

