
TY  - JOUR
A1  - Katritzky, AR 
A1  - Wrobel, L 
A1  - Savage, GP 
A1  - Deyrupdrewniak, M 
T1  - The Formation of Ketones by a Reaction Equivalent to R<sup>-</sup>+R&#8242;COCH<sub>2</sub><sup>+</sup>&#8594;R&#8242;COCH<sub>2</sub>R
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1990
VL  - 43
IS  - 1
SP  - 133
EP  - 139
KW  - 
UR  - https://doi.org/10.1071/CH9900133 
N2  - A general method has been developed for the overall transformation of &#945;- bromo ketones to &#945;-alkyl or &#945;-aryl ketones , with benzotriazole being used as a synthetic auxiliary. &#945;- Benzotriazolyl ketones , when converted into their phenylhydrazones, reacted smoothly with alkyl and aryl Grignard reagents, which displaced benzotriazolate, to give the corresponding &#945;-alkyl or &#945;-aryl hydrazones. In some cases, these hydrolysed directly to the &#945;-alkyl or &#945;-aryl ketones. In each case, the product was treated with 2,4-dinitrophenylhydrazine to isolate the target ketones as the corresponding 2,4-dinitrophenylhydrazones. 
ER  -

