
%0 Journal Article
%A Roitman, JN 
%A Wong, RY 
%T Revised Absolute Configurations of Latifolic Acid and the Pyrrolizidine Alkaloid Latifoline
%J Australian Journal of Chemistry
%D 1988/11/01
%V 41
%N 11
%P 1781-1787
%K 
%R https://doi.org/10.1071/CH9881781
%U https://www.publish.csiro.au/paper/CH9881781 
%X The absolute stereochemistry of (+)- latifolk acid has been determined by single-crystal X-ray crystallographic analysis to be (2S,3R,4R)-3- hydroxy-2,4-dimethyl-5-oxotetrahydrofuran-3-carboxylic acid. The configuration of the three chiral  centres is opposite to that presently recorded in the literature. Accordingly, the configuration of the pyrrolizidine alkaloid, latifoline, which includes a latifolic acid side chain, must be revised. 
