
TY  - JOUR
A1  - Clezy, PS 
A1  - Duncan, MW 
A1  - Smythe, GA 
T1  - Preparation of a Deuterated Analog of Tetrahydropapaveroline Suitable for Use as an Internal Standard for G.C./M.S. Analysis of This Alkaloid: Retro Pictet-Spengler Condensation
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1988
VL  - 41
IS  - 4
SP  - 483
EP  - 491
KW  - 
UR  - https://doi.org/10.1071/CH9880483 
N2  - Attempts to prepare deuterated analogues of salsolinol and tetrahydropapaveroline by exchange procedures in D2O have demonstrated that the Pictet-Spengler reaction is a reversible process. Tetrahydropapaveroline can be readily obtained from papaverine by reduction with Zn/HCl followed by demethylation in a process which can conveniently be adapted to produce a (2H3)analogue. 
ER  -

