
TY  - JOUR
A1  - Cannon, JR 
A1  - Matsuki, Y 
A1  - Patrick, VA 
A1  - White, AH 
T1  - Selective O-Demethylation of 5,8-Dihydroxy-2,3-Dimethoxy-6-Methylnaphtho-1,4-Quinone: The Crystal Structures of 5,8-Dihydroxy-2,3-Dimethoxy-6-Methylnaphtho-1,4-Quinone and 2,5,8-Triacetoxy-3-Methoxy-6-Methylnaphtho-1,4-Quinone
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1987
VL  - 40
IS  - 7
SP  - 1191
EP  - 1200
KW  - 
UR  - https://doi.org/10.1071/CH9871191 
N2  - It has been confirmed that treatment of 5,8-dihydroxy-2,3-dimethoxy-6-methylnaphtho-1,4- quinone (1) with dilute aqueous sodium hydroxide leads to selective O- demethylation. The hydrolysis product has been identified as 2,5,8-trihydroxy-3-methoxy-6-methylnaphtho1,4- quinone (3) from the crystal structure of the corresponding triacetate (4). The crystal structures of 5,8-dihydroxy-2,3-dimethoxy-6-methylnaphtho-1,4-quinone (1) and 2,5,8-triacetoxy-3-methoxy-6-methylnaphtho-1,4-quinone (4) were determined by X-ray diffraction; diffractometer data at 295 K were refined by least squares techniques to residuals of 0.074 (583 'observed' reflections) for (1) and 0.049 (2005) for (4). Crystals of (1) are monoclinic, P2l/c, a 3.873(4), b 20.21(1), c 15.OO(2) Å, &#946; 96.05(6)º, Z 4. Crystals of (4) are also monoclinic, P2l/c, a 10.532(5), b 14.596(6), c 12.097(6) Å, &#946; 109.74(4)º, Z 4. 
ER  -

