
TY  - JOUR
A1  - Deady, LW 
A1  - Werden, DM 
T1  - Nucleophilic-Substitution Reactions in Benzo[C][1,8]Naphthyridines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1986
VL  - 39
IS  - 4
SP  - 667
EP  - 675
KW  - 
UR  - https://doi.org/10.1071/CH9860667 
N2  - The reactions of 1-chloro-3-methyl-6-(p- methylphenoxy ) benzo [c][1,8] naphthyridine with a variety of nucleophiles are reported. The relative reactivity of the 1- and 6-positions depends on the nucleophile and reaction conditions. Anilines, and alkyl and aryl thioxides react at position 1, alkylamines and alkoxide at position 6, and acidified alcohol at both 1 and 6. Some possible reasons for these positional reactivities are discussed. 
ER  -

