
%0 Journal Article
%A Barlin, GB 
%A Brown, DJ 
%A Cronin, BJ 
%A Ngu, M 
%T Heterocyclic Amplifiers of Phleomycin .X. Derivatives of Diazine Mono-Thiol and Di-Thiol
%J Australian Journal of Chemistry
%D 1986/01/01
%V 39
%N 1
%P 69-75
%K 
%R https://doi.org/10.1071/CH9860069
%U https://www.publish.csiro.au/paper/CH9860069 
%X A series of pyrazinethiols and pyrimidinethiols with phenyl substituents have been prepared and converted into their carbamoylmethylthio, 2-dimethylaminoethylthio and 2-aminoethylthio derivatives. Similar derivatives of pyrazine-2,3- and -2,6-dithiol were also prepared together with N,N-dimethyl-2-(1&#8242;- and 2&#8242;- naphthyloxy)ethylamine. As amplifiers of phleomycin these compounds showed moderate two-to- three-star activity. 
