
TY  - JOUR
A1  - Allan, RD 
A1  - Dickenson, HW 
A1  - Johnston, GAR 
A1  - Kazlauskas, R 
A1  - Tran, HW 
T1  - Synthesis of Analogues of GABA. XIV. Synthesis and Activity of Unsaturated Derivatives of 5-Aminopentanoic Acid (d-Aminovaleric Acid)
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1985
VL  - 38
IS  - 11
SP  - 1651
EP  - 1656
KW  - 
UR  - https://doi.org/10.1071/CH9851651 
N2  - The (Z) and (E) pairs of 5-aminopent-2-enoic acid and 5-aminopent-3- enoic acid, as well as the related 5-aminopent-3-ynoic acid, have been prepared for structure-activity studies on GABA receptors. Only the (Z) isomers were active as GABA agonists with (Z)-5-aminopent-2-enoic acid being two- to four-fold more active than 5-aminopentanoic acid. 
ER  -

