TY - JOUR A1 - Russell, RA A1 - Irvine, RW A1 - Warrener, RN T1 - Anthracyclines. XIII The Synthesis of (+)-(4R,6R)- and (+)-(4S,6R)-6-Acetyl-6-(t-butyldimethylsilyloxy)-4-ethoxy-4-methoxy-5,6,7,8-tetrahydronaphthalen-1(4H)-one: New Chiral AB Synthons for the Synthesis of (—)-7-Deoxydaunomycinone JF - Australian Journal of Chemistry JO - Aust. J. Chem. Y1 - 1985 VL - 38 IS - 1 SP - 189 EP - 195 KW - UR - https://doi.org/10.1071/CH9850189 N2 - The title dienones have been prepared from (-)-(2R,1′S)-8-benzyloxy-2-(1′-hydroxyethyl)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-ol, by a series of reactions in which the selective cleavage of an aryl methyl ether in the presence of an aryl ethyl ether plays a key role. This 10- step sequence proceeds in an overall yield of 55%, and chiral integrity is preserved throughout. ER -