
TY  - JOUR
A1  - Marcuccio, SM 
A1  - Elix, JA 
T1  - Pyrazine chemistry. II. Reduction of 3,6-Dibenzylidenepiperazine-2,5-diones
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1984
VL  - 37
IS  - 8
SP  - 1791
EP  - 1794
KW  - 
UR  - https://doi.org/10.1071/CH9841791 
N2  - A reinvestigation of the reduction of 3,6-dibenzylidenepiperazine-2,5-dione (1) with zinc and acetic acid established that this reaction gave (Z)-6-benzyl-3-benzylidenepiperazine-2,5-dione (10). When a mixture of acetic acid and hydrochloric acid was used in the reduction, a mixture of trans- (12) and cis-3,6-dibenzylpiperazine-2,5-dione (5) was obtained. Direct catalytic reduction of 3,6-di(2-chloro- benzy1idene)piperazine-2,5-dione (2) to (±)-cis-3,6-di(2-chlorobenzyl)piperazine-2,5-dione (6) was also accomplished. 
ER  -

