
TY  - JOUR
A1  - Deady, LW 
T1  - A synthesis of Benzo[c][1,8]naphthyridinones: an exception to the Knorr reaction
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1984
VL  - 37
IS  - 5
SP  - 1135
EP  - 1138
KW  - 
UR  - https://doi.org/10.1071/CH9841135 
N2  - The reaction of 1-methoxyisoquinolin-3-amine with ethyl acetoacetate, and subsequent ring closure, is reported. Conrad-Limpach synthesis leads to the expected 4(1H)-one. The same isomer is formed under Knorr conditions (hot polyphosphoric acid), while a less acidic medium (hot acetic acid) gives the 2(1H)-one. 
ER  -

