
TY  - JOUR
A1  - Allan, RD 
A1  - Fong, J 
T1  - Synthesis of analogues of GABA. X. The bicyclic &#946;-diketone Octahydro-1H-2-pyrindine-5,7-dione
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1983
VL  - 36
IS  - 6
SP  - 1221
EP  - 1226
KW  - 
UR  - https://doi.org/10.1071/CH9831221 
N2  - The synthesis is described of octahydro-1H-2-pyrindine-5,7-dione (4) and its 6-diazo and 6-bromo derivatives. These are analogues of GABA in which the carboxyl group is replaced by an enolic &#946;-diketone. The compounds showed negligible or very weak activity as GABA agonists with respect to inhibition of [3H] GABA binding, uptake and transamination in rat brain membranes. 
ER  -

