
TY  - JOUR
A1  - Mcfarlane, EF 
A1  - Martinic, C 
T1  - 400-MHz <sup>1</sup>H N.M.R. of adjuvant muramyl dipeptide in dimethyl sulfoxide
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1983
VL  - 36
IS  - 6
SP  - 1087
EP  - 1096
KW  - 
UR  - https://doi.org/10.1071/CH9831087 
N2  - The minimal active principle, N-acetylmuramyl-L-alanyl-D-isoglutamine* (MDP), of complete Freund's adjuvant was studied in dry dimethyl sulfoxide solutions by 1H n.m.r. at 400 MHz. All resonances except those of the non-anomeric CH protons of the sugar ring were assigned. The &#945;/&#946; anomeric ratio was found to be the same (2 : 1) as reported for the equilibrated aqueous solutions from which the dimethyl sulfoxide solutions were prepared. The present findings indicate that MDP adopts a substantially structured conformation in dimethyl sulfoxide solutions. 
ER  -

