
TY  - JOUR
A1  - Kuniyoshi, M 
A1  - Satoh, Y 
T1  - The chlorination of 5&#x3b1;- and 5&#x3b2;-cholestan-3-one and dechlorination of 2,2,4&#x3b1;-trichloro-5&#x3b1;-cholestan-3-one and 2&#x3b2;,4,4-trichloro-5&#x3b2;-cholestan-3-one
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1983
VL  - 36
IS  - 5
SP  - 1073
EP  - 1078
KW  - 
UR  - https://doi.org/10.1071/CH9831073 
N2  - Chlorination of S&#x3b1;- and 5&#x3b2;-cholestan-3-one (l) and (7) proceeds sequentially to give the &#x3b1;-monochloro (2) and (8), &#x3b1;,&#x3b1;-dichloro (3) and (9), and &#x3b1;, &#x3b1;, &#x3b1;'-trichloro (4) and (10) derivatives; the nature of the product mainly depends on the reaction conditions. The &#x3b1;, &#x3b1;'-dichloro ketones (5) and (11) could be prepared by dechlorination of the corresponding trichloro ketones (4) and (10) with chromium(II) acetate. Further dechlorination of the dichloro ketones (5) and (11) with the same reagent furnished the &#x3b1;-monochloro ketones (6) and (12) which cannot be obtained by the direct chlorination of 5&#x3b1;- and 5&#x3b2;-cholestan-3-one. 
ER  -

