
TY  - JOUR
A1  - Kirkpatrick, A 
A1  - Maclaren, JA 
T1  - Synthesis of 1,2,3,4-Tetrahydro-&#946;-carbolines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1983
VL  - 36
IS  - 4
SP  - 833
EP  - 838
KW  - 
UR  - https://doi.org/10.1071/CH9830833 
N2  - 1,1-Disubstituted 1,2,3,4-tetrahydro-&#946;-carbolines are formed by the action of trifluoroacetic acid on enamines derived from tryptamine or tryptophan. With methanolic hydrogen chloride, either cyclization to the corresponding &#946;-carboline derivative, or acidolysis to regenerate the parent amine, occurs. The course of this reaction depends on the substitution pattern. Mixtures of products are not formed. Authentic phenacyl L-tryptophanate hydrochloride has been synthesized. 
ER  -

