
%0 Journal Article
%A Caselli, AS 
%A Collins, DJ 
%A Stone, GM 
%T The structure and function of oestrogens. III. 3,17&#946;-Dihydroxy-6-oxaoestra-1,3,5(10),8(9)-tetraen-7-one and related steroidal coumarins
%J Australian Journal of Chemistry
%D 1982/04/01
%V 35
%N 4
%P 799-808
%K 
%R https://doi.org/10.1071/CH9820799
%U https://www.publish.csiro.au/paper/CH9820799 
%X A Pechmann condensation of resorcinol, or resorcinol monomethyl ether with ethyl t-7a-methyl- 1,5-dioxo-r-3a,4,5,6,7,7a-hexahydroindan-c-4-carboxylate (10b) gave 3-hydroxy-6-oxaoestra- 1,3,5(10),8(9)-tetraene-7,17-dione (3a), or the corresponding 3-methoxy compound (3b), respectively. Reduction of 3-hydroxy-6-oxaoestra-1,3,5(10),8(9)-tetraene-7,17-dione (3a) with sodium borohydride gave 3,17&#946;-dihydroxy-6-oxaoestra-1,3,5(10),8(9)-tetraen-7-one (11). Compounds (3a) and (11) were tested for oestrogenic activity. 
