
%0 Journal Article
%A Armarego, WLF 
%A Reece, PA 
%T Quinazolines. XXV. The synthesis of 8-Chloro-2-[4-(2-furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine hydrochloride (8-chloroprazosin hydrochloride)
%J Australian Journal of Chemistry
%D 1981/07/01
%V 34
%N 7
%P 1561-1566
%K 
%R https://doi.org/10.1071/CH9811561
%U https://www.publish.csiro.au/paper/CH9811561 
%X A twelve-step synthesis of 8-chloroprazosin (3) hydrochloride starting from vanillin has been achieved in 16% overall yield (59% w/w yield). The hydrochloride is a useful internal standard for the quantitative estimation of the drug prazosin in human plasma. 
