
%0 Journal Article
%A Brown, DJ 
%A Strekowski, L 
%T Hilbert-Johnson reactions of 2,2',4',6-Tetramethoxy-4,5'-bipyrimidine
%J Australian Journal of Chemistry
%D 1981/05/01
%V 34
%N 5
%P 1157-1160
%K 
%R https://doi.org/10.1071/CH9811157
%U https://www.publish.csiro.au/paper/CH9811157 
%X 2,2',4',6-Tetramethoxy-4,5'-bipyrimidine (1) was converted successively by methyl iodine into 2,4',6-trimethoxy-l'-methyl-4,5'-bipyrimidin-2'-one (2a), a single dimethoxy-1,1'-dimethyl-4,5'-bipyrimidinedione (3 or 4; not positively identified), 4'-methoxy-1,1',3-trimethyl-4,5'-bipyrimidine- 2,2',6-trione (5) and 1,1',3,3'-tetramethyl-4,5'-bipyrimidine-2,2,4',6-tetrone (6e). Hydrolysis of the first three products gave respectively, the 1'-methyl, 1,1'-dimethyl and 1,1',3-trimethyl derivatives (6b-d) of 4,5'-bipyrimidine-2,2',4',6-tetrone. Structures were elucidated by n.m.r., ultraviolet and mass spectra. 
