
%0 Journal Article
%A Baldas, J 
%A Colmanet, S 
%A Porter, QN 
%T The tritium kinetic isotope effect for the iodination of L-(5-<sup>3</sup>H)-3-Iodotyrosine
%J Australian Journal of Chemistry
%D 1981/05/01
%V 34
%N 5
%P 1147-1151
%K 
%R https://doi.org/10.1071/CH9811147
%U https://www.publish.csiro.au/paper/CH9811147 
%X The kinetic tritium isotope effect (kH/kT) for the iodination of L-(5-3H)-3-iodotyrosine at pH 7&#903;5 was found to be 4&#903;29±0.25 with molecular iodine and 4&#903;50±0.26 with chloramine-T/potassium iodide. This effect establishes that the rate-limiting step is proton removal by the general base. A novel method for measuring the fraction of tritiated water by high performance liquid chromatography is described. 
