
%0 Journal Article
%A Browne, EJ 
%A Skelton, BW 
%A White, AH 
%T Bischler-Napieralski reaction of N-(4-Aryl-4-hydroxybutyl)benzamides: Synthesis and X-ray structure of (E)-3-arylmethylidene-4,5-dihydro-3H-pyrroles
%J Australian Journal of Chemistry
%D 1981/04/01
%V 34
%N 4
%P 897-904
%K 
%R https://doi.org/10.1071/CH9810897
%U https://www.publish.csiro.au/paper/CH9810897 
%X The N-(4-aryl-4-hydroxybuty1)benzamides (3a,b) have been cyclized under Bischler-Napieralski conditions to the 3-arylmethylidene-4,5-dihydro-3H-pyrroles (4a,b). These products are consistent with the formation of N-(4-aryibut-3-enyl)benzamide intermediates. The structure of the 3,4-dimethoxyphenyl derivative (4a) was confirmed by X-ray crystallographic analysis, which established its configuration as the E-isomer. 
