
%0 Journal Article
%A Kazlauskas, R 
%A Lidgard, RO 
%A Murphy, PT 
%A Wells, RJ 
%A Blount, JF 
%T Brominated tyrosine-derived metabolites from the sponge <I>Ianthella basta</I>
%J Australian Journal of Chemistry
%D 1981/04/01
%V 34
%N 4
%P 765-786
%K 
%R https://doi.org/10.1071/CH9810765
%U https://www.publish.csiro.au/paper/CH9810765 
%X Seven novel metabolites, each originating from four bromotyrosine units, have been isolated from the sponge Ianthella basta. Bastadin-1 (2), bastadin-2(3) and bastadin-3(4) are derived from a single phenol oxidative coupling whilst the macrocyclic compounds bastadin-4(5), bastadin-5(6), bastadin-6(8) and bastadin-7(7) are formed by two phenol oxidative coupling reactions. Compounds (2)-(8) showed potent in vitro antimicrobial activity against Gram-positive organisms. 
