
TY  - JOUR
A1  - Stewart, FHC 
T1  - Synthesis of L-Kynurenine peptides conducted without masking the side-chain amino group
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1980
VL  - 33
IS  - 3
SP  - 633
EP  - 640
KW  - 
UR  - https://doi.org/10.1071/CH9800633 
N2  - Various free L-kynurenine peptides, including an analogue of the opiate agonist leucine-enkephalin, have been synthesized by using the N&#945;-t- butyloxycarbonyl derivative of L-kynurenine as a key precursor. By selecting appropriate mild conventional coupling procedures it was possible to carry out the synthetic operations without having to mask the side-chain amino group in any way, but intramolecular acylation with formation of a seven-membered lactam could be demonstrated under more vigorous conditions. 
ER  -

