
%0 Journal Article
%A Black, DSC 
%A Gatehouse, BMKC 
%A Theobald, F 
%A Wong, LCH 
%T Investigation of the Bischler indole synthesis from 3,5-dimethoxyaniline
%J Australian Journal of Chemistry
%D 1980/02/01
%V 33
%N 2
%P 343-350
%K 
%R https://doi.org/10.1071/CH9800343
%U https://www.publish.csiro.au/paper/CH9800343 
%X Cyclization of the amino ketones (3a,b) derived from 3,5- dimethoxyaniline, and phenacyl bromide and 4-bromophenacyl bromide respectively, afforded 2-arylindoles (8a,b) in preference to 3-aryl- indoles(7). The 3-(4'-bromophenyl)indole (7b) was also isolated in the presence of polyphosphoric acid, but not when amine hydrochloride catalysis was employed. The structure of 2-(4'-bromophenyl)-4,6- dimethoxyindole (8b) was confirmed by X-ray diffraction studies. 
