
TY  - JOUR
A1  - Angyal, SJ 
A1  - Nicholls, RG 
A1  - Pinhey, JT 
T1  - Steric Effects on the Iodide-Induced Elimination of 2- and 3-Methanesulfonyloxy Groups from 5&#945;-Cholestane Derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1979
VL  - 32
IS  - 11
SP  - 2433
EP  - 2440
KW  - 
UR  - https://doi.org/10.1071/CH9792433 
N2  - Contrary to earlier reports on closely related compounds, the reaction of all four diastereomers of 5&#945;-cholestane-2,3-diol bismethanesulfonate with sodium iodide gives 5&#945;-cholest-2-ene. The rate of the reaction decreases in the order 2&#945;,3&#945; > 2&#945; 3&#946; » 28,3&#945; &#8776; 2&#946;,3&#946;. The reactions of the 5&#945;-cholestan-2- and -3-yl methanesulfonates with sodium iodide were also investigated. The relative reaction rates are explained by considering the steric effects of the substituents. 
ER  -

