
TY  - JOUR
A1  - Christie, RM 
A1  - Rickards, RW 
A1  - Watson, WP 
T1  - Microbial transformation of cannabinoids. I. Metabolism of (&#8211;)-&#916;<sup>9</sup>-6a,10a-<I>trans</I>-Tetrahydrocannabinol by <I>Chaetomium globosum</I>
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1978
VL  - 31
IS  - 8
SP  - 1799
EP  - 1807
KW  - 
UR  - https://doi.org/10.1071/CH9781799 
N2  - Chaetomium globosum isolated from Cannabis sativa plant material converts (-)-&#916;9-6a,10a-frans-tetrahydrocannabinol (&#916;9-THC) (1a) into a number of metabolic products, which include the 3'-hydroxy, 11-hydroxy and 3',11-dihydroxy derivatives (1c), (1b) and (1d) respectively. The structure of the 3'-hydroxy-&#916;9-THC (1c) has been confirmed by synthesis, whilst the structure of the 3',11-dihydroxy-&#916;9-THC (1d) follows from mass spectroscopic comparison with the 3'-hydroxy and 11-hydroxy derivatives. 
ER  -

