
TY  - JOUR
A1  - Gainsford, AR 
A1  - Sargeson, AM 
T1  - Stereoselective and regioselective condensation reactions of coordinated aminoacetone
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1978
VL  - 31
IS  - 8
SP  - 1679
EP  - 1688
KW  - 
UR  - https://doi.org/10.1071/CH9781679 
N2  - Treatment of cis-[Co(en)2(NH2CH2R)(NH2CH2COCH3)]3+ ions (R = H, Me, CH2Br, Ph, p-C6H4Cl) with base leads to imine complexes where the coordinated aminoacetone has reacted with a bound monoamine RNH2 or an ethylenediamine moiety. The product distribution appears to be determined by the relative acidity of the monoamine and the ethylenediamine amine centres; condensation is preferred at the most acidic site. Reduction of the imine group in these complexes with BH4- ion leads to new complexes of the type [Co(en)2(NH2CH2CH(Me)NHCH2R)]3+ and [Co(en)(NH2CH2CH2NHCH(Me)CH2NH2)(NH2CH2R)]3+ in which the reduced ligand is synthesized stereospecifically. 
ER  -

