
TY  - JOUR
A1  - Murray, KS 
A1  - Newman, PJ 
A1  - Gatehouse, BM 
A1  - Taylor, D 
T1  - Structure, absolute configuration and electrochemical properties of Tris(N-methylformothiohydroxamato)iron(III), an antibacterial metal chelate and potential iron siderochrome
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1978
VL  - 31
IS  - 5
SP  - 983
EP  - 992
KW  - 
UR  - https://doi.org/10.1071/CH9780983 
N2  - The title compound, which previously had been isolated from bacteria and shown to possess anti-bacterial activity, has been chemically synthesized. The molecular structure has a cis (facial) arrangement of the asymmetric {S,O} bidentate ligands (Fe-S 2.441(1) &#506;, Fe-O 2.010(1) &#506;) as required by the crystallographic C3 molecular symmetry. (Crystal data: C6H12N3O3S3Fe, rhombohedral, space group R3, a 7.094(2)&#506;, &#945; 102.00(1)&#176;, Z 1.) The complex was spontaneously resolved into enantiomers on crystallization and the absolute configuration in the crystal studied was established as &#923; by the anomalous dispersion technique. Magnetic, e.s.r. and Mossbauer studies are compatible with a distorted octahedral complex of high-spin iron(III). Cyclic voltammetric studies in acetone of the title compound and some related iron(III) thiohydroxamates were carried out. A reversible FeIII/FeII reduction wave was observed for the N-methylformothiohydroxamato chelate, in contrast to the irreversible reduction of tris(benzohydroxamato)iron(III), a related complex containing an {O,O} chelate. The tris(benzothiohydroxamato) chelate, Fe(PhC(S)NHO)3, which possesses a non-alkylated nitrogen, also showed an irreversible reduction wave. 
ER  -

