
TY  - JOUR
A1  - Richards, CM 
A1  - Hofmann, A 
T1  - Pyridone analogues of tetrahydroisoquinolines and protoberberines from mimosine and mimosinamine
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1978
VL  - 31
IS  - 1
SP  - 187
EP  - 191
KW  - 
UR  - https://doi.org/10.1071/CH9780187 
N2  - Several pyrido[1,2-a]piperazines and their N-methyl derivatives have been prepared. These pyridine analogues of the 1,2,3,4-tetrahydroisoquinolines were formed by condensation of carbonyl compounds with mimosine and mimosinamine in the absence of an acid catalyst. A Mannich reaction converted one of these compounds, 1-(3,4-dimethoxybenzyl)-9-hydroxy-1,2,3,4-tetrahydro-8H-pyrido[1,2-a]- pyrazin-8-one, into a pyridone analogue of the tetrahydroprotoberberine caseadine. 
ER  -

