
%0 Journal Article
%A Pasaribu, SJ 
%T Synthesis of the major encephalitogenic determinant of myelin basic protein and the <sup>13</sup>C N.M.R. of some protected intermediates
%J Australian Journal of Chemistry
%D 1977/11/01
%V 30
%N 11
%P 2533-2544
%K 
%R https://doi.org/10.1071/CH9772533
%U https://www.publish.csiro.au/paper/CH9772533 
%X The main encephalitogenic determinant of bovine myelin basic protein (MBP 114-122) has been synthesized through fragment condensation of tetrapeptide, Boc-Phe-Ser-Trp-Gly-OH, and penta-peptide, H-Ala- Glu(OBzl)-Gly-Gln-Lys(N&#949;-Cbz)-Obzl. It was observed that the benzyl ether protecting group of the serine side chain was not removed during catalytic hydrogenation (Pd/C-H2) of the tetrapeptide, Boc-Phe- Ser(OBzl)-Trp-Gly-OBzl. 13C N.M.R. spectra of some other intermediates are discussed. 
