
%0 Journal Article
%A Maclaren, JA 
%T The reaction of tryptophan and derivatives with some 1,3-dicarbonyl compounds
%J Australian Journal of Chemistry
%D 1977/09/01
%V 30
%N 9
%P 2045-2051
%K 
%R https://doi.org/10.1071/CH9772045
%U https://www.publish.csiro.au/paper/CH9772045 
%X Enamine methyl esters are obtained by methylation of the condensation product from a 1,3-dicarbonyl compound with L-tryptophan, or directly from methyl L-tryptophanate and the 1,3-dicarbonyl compound. Protonation of these enamines forms either methyl L-tryptophanate or a tetrahydro-&#946;-carboline derivative (two diastereomers in certain cases), depending on the structure of the dicarbonyl compound. Enamines from 1,3-dicarbonyl compounds and tryptamine yield similar cyclic products on protonation. 
