
%0 Journal Article
%A Philp, RP 
%A Robertson, AV 
%T Cyclic hydroxycarboxylic acids. II. Lactonization reactions on 2-Hydroxycyclopentanecarboxylic acids and 3-Hydroxyprolines
%J Australian Journal of Chemistry
%D 1977/01/01
%V 30
%N 1
%P 123-130
%K 
%R https://doi.org/10.1071/CH9770123
%U https://www.publish.csiro.au/paper/CH9770123 
%X The racemates of cis-2-hydroxycyclopentanecarboxylic acid and of cis-3- hydroxy-N-tosylproline yield corresponding &#946;-lactones upon treatment with cold tosyl chloride-pyridine. Similar treatment of trans-2- hydroxycyclopentanecarboxylic acid gives cyclopent-1-enecarboxylic acid, but trans-3-hydroxy-N-tosylproline is unchanged. Unlike in other 3-hydroxyprolines, the proline protons in the N-tosyl &#946;-lactone have a completely first-order p.m.r. spectrum which is analysed. 
