
TY  - JOUR
A1  - Duong, T 
A1  - Prager, RH 
A1  - Tippett, JM 
A1  - Ward, AD 
A1  - Kerr, DIB 
T1  - Central nervous system active compounds. II. The synthesis of some 4-, 5-, 6- and 7-substituted caprolactams
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1976
VL  - 29
IS  - 12
SP  - 2667
EP  - 2682
KW  - 
UR  - https://doi.org/10.1071/CH9762667 
N2  - The synthesis of caprolactam derivatives substituted at C4, C5, C6 and C7 with alkyl, aryl, acyl and hetero substituents is described. A variety of synthetic approaches to these compounds have been investigated and assessed, particularly for the synthesis of C4- and C6-substituted compounds. A significant number of the C4-, C6- and C7- substituted compounds prepared show central nervous system activity, ranging from convulsants to depressants depending on the position and nature of the substituent group. 
ER  -

