
TY  - JOUR
A1  - Deady, LW 
A1  - Stillman, DC 
T1  - Steric effects in quaternizations. Alkylation of pyridine, thiazole, isothiazole and some benzologues with methyl, ethyl and isopropyl iodides
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1976
VL  - 29
IS  - 8
SP  - 1745
EP  - 1748
KW  - 
UR  - https://doi.org/10.1071/CH9761745 
N2  - Results of quaternization reactions in sulpholane at 65º are reported. A large steric hindrance is noted for quinoline relative to pyridine. A much smaller variation in rate with change in alkyl halide is seen in the benzothiazole/thiazole pair. Steric effects are very small and the rate retardation resulting from benzofusion is ascribed largely to an electronic effect. 2,l-Benzisothiazole reacts at essentially the same rate as isothiazole under these conditions. 
ER  -

