
TY  - JOUR
A1  - Pojer, PM 
A1  - Rae, ID 
T1  - Synthesis of 2-Benzamido-2-mercaptopropanoic acid from 4-Methyl-2-phenyl-2-oxazolin-5-one
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1972
VL  - 25
IS  - 8
SP  - 1737
EP  - 1749
KW  - 
UR  - https://doi.org/10.1071/CH9721737 
N2  - The structures of the dimers of N-substituted pyruvamides are confirmed to be the pyrrolidinones (6). 4-Chloro-4-methyl-2-phenyl-2-oxazolin-5-one reacts with a-toluenethiol to give a thiol ester which can be converted into 2-benzamido-2-benzyl-thiopropanoic acid. Reaction of the chlorooxazolinone with thioacetic acid gives 4-acetylthio-4-methyl-2-phenyl-2-oxazolin-one which is converted into 2-benzamido-2-mercaptopropanoic acid. The mercapto acid is oxidized by iron(111) chloride-ether to a mixture of disulphides. 
ER  -

