
TY  - JOUR
A1  - Stewart, FHC 
T1  - Use of N-2-cyanoethylglycine derivatives in the synthesis of peptides of N-2-carboxamidoethylglycine, an isomer of glutamine
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1971
VL  - 24
IS  - 6
SP  - 1267
EP  - 1275
KW  - 
UR  - https://doi.org/10.1071/CH9711267 
N2  - Derivatives of N-2-cyanoethylglycine have been employed as coupling components in the synthesis of protected peptides. The nitrile group in N-2-cyano-ethylglycine is readily hydrated by hydrogen bromide treatment with formation of N-2-carboxamidoethylglycine, which is an isomer of glutamine. This reaction, conducted on cyanoethyl intermediates with simultaneous cleavage of appropriate acid-labile protecting groups, was utilized to prepare several free peptides containing N-2-carboxamidoethylglycine residues. 
ER  -

