
TY  - JOUR
A1  - Brown, DJ 
A1  - Sugimoto, T 
T1  - Aza-analogues of pteridine. III. Some monomethoxy-1,2,4,6,8-pentaazanaphthalenes and related compounds
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1971
VL  - 24
IS  - 3
SP  - 633
EP  - 643
KW  - 
UR  - https://doi.org/10.1071/CH9710633 
N2  - 4-Hydrazino-2-methoxy-6-methyl-5-nitropyrimidine reacted with triethyl orthoformate to give the ethoxymethylenehydrazino analogue or 4-methoxy-6-methyl-7-nitro-1,2,3a,5-tetraazaindene according to conditions. The first of these products was converted by reductive cyclization and subsequent dehydrogenation into 7-methoxy-5-methyl- 1,2,4,6,8-pentaazanaphthalene. Attempts to hydrolyse this and related compounds to the corresponding 7-hydroxypentaazanaphthalenes failed and direct approaches via appropriate 2-hydroxypyrimidines gave only 4- hydroxy-7-nitrotetraazaindenes.     5-Alkoxypentaazanaphthalenes were prepared via 1,2-dihydropentaaza- naphthalene or its 5-chloro derivative. Nucleophilic displacements were used to make the 5-hydroxy, 5-methylthio, 5-diethylamino, and other analogues from 5-methoxy-3-methylpentaazanaphthalene.     The ionization constants, ultraviolet spectra, and proton magnetic resonance spectra of members of both bicyclic series are tabulated and discussed. 
ER  -

