
TY  - JOUR
A1  - Johnston, GAR 
T1  - Approaches to the preparation of 3'-deoxynucleosides
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1968
VL  - 21
IS  - 2
SP  - 513
EP  - 519
KW  - 
UR  - https://doi.org/10.1071/CH9680513 
N2  - The stability of 3'-O-sulphonyl derivatives of uridine towards nucleophilic displacement indicates that sulphonate replacement is unlikely to offer a general route to 3'-deoxynucleosides. The preparation of 3'-deoxyuridine by direct iodination of 2',5'-di-O-trityluridine with triphenylphosphite methiodide followed by catalytic hydrogenolysis is discussed as such a general route dependent on the availability of suitably protected nucleoside starting materials. Acyl migration takes place under the conditions of the iodination reaction, limiting the choice of protecting groups. 
ER  -

