
TY  - JOUR
A1  - Hudson, CB 
A1  - Robertson, AV 
T1  - Reactions of 3,4-dehydroproline and 4-chloroprolines with ninhydrin, isatin, and cyclic &#945;-diketones
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1967
VL  - 20
IS  - 7
SP  - 1511
EP  - 1520
KW  - 
UR  - https://doi.org/10.1071/CH9671511 
N2  - 3,4-Dehydro-DL-proline reacts with a number of a-dicarbonyl compounds to form products in which the pyrroline ring is converted into an N- substituted pyrrole. Depending on the reactivity of the &#945;-dicarbonyl compound, a second molecule may (e.g. ninhydrin) or may not (e.g, isatin) react further by &#945;-substitution of the pyrrole. The structures of the products account for the different colour reactions of dehydroproline compared with proline. cis- and trans-4-Chloro-L-proline yield the same products as dehydroproline with ninhydrin and isatin. 
ER  -

