
%0 Journal Article
%A Brown, DJ 
%A Forster, RV 
%T Pyrimidine reactions. XIV. The butylaminolysis of substituted methoxy-and methylthio-pyrimidines
%J Australian Journal of Chemistry
%D 1966/12/01
%V 19
%N 12
%P 2321-2330
%K 
%R https://doi.org/10.1071/CH9662321
%U https://www.publish.csiro.au/paper/CH9662321 
%X Aminolyses of 2- and 4-methoxy (or methylthio) pyrimidines bearing C- methyl, CC?-dimethyl, 5-bromo, or 5-nitro substituents have proved of value, in the absence of added solvent, for preparing the corresponding n- and t-butyl-aminopyrimidines. When these displacements are followed spectrometrically, the apparent first-order rate constants indicate mild deactivation by additional methyl substituents, moderate activation by a bromo substituent, and profound activation by a nitro substituent. Ionization constants and ultraviolet spectra of relevant pyrimidines are recorded. 
