
TY  - JOUR
A1  - Barnes, CS 
A1  - Beilby, BD 
T1  - Methylsteroids. VII. Factors Affecting the Hydrolysis of 7&#945;- and 11&#946;-Acetoxylanostanes
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1961
VL  - 14
IS  - 1
SP  - 48
EP  - 56
KW  - 
UR  - https://doi.org/10.1071/CH9610048 
N2  - Doubly bonded methylene groups have been introduced into 7&#945;- and 11&#946;-acetoxylanostanes and the rate of hydrolysis compared with compounds having a hydroxy or carbonyl group at the same position as the methylene group. It was found that methylene groups facilitate hydrolysis of the hindered acetoxy groups in the same way, but not to the same extent, as carbonyl groups. It is concluded that the facilitation in each case results from a conformational disturbance, but that there is some other factor involved in carbonyl facilitation. It was not possible to demonstrate a similar effect resulting from steric crowding of substituents. 
ER  -

