
TY  - JOUR
A1  - Cymerman-Craig, J 
A1  - harrisson, RJ 
T1  - Synthetic Antispasmodics. I. Some 1,1-Diaryl-3-(4'-methyl-1'-piperazino)-1-propenes
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1955
VL  - 8
IS  - 3
SP  - 378
EP  - 384
KW  - 
UR  - https://doi.org/10.1071/CH9550378 
N2  - The Mannich bases obtained by reaction of 1-methylpiperazine and formaldehyde with acetophenone and 2-acetylthiophen respectively have been condensed with phenyl- and &#945;-thienylmagnesium bromide, giving the 1,1-diphenyl, 1,1-di-&#945;-thienyl, and 1-phenyl-1-&#945;-thienyl-3-(4'-methyl-1'-piperazino)propan-1-ols. These have been dehydrated to the corresponding 1-propenes. Both the propanols and the propenes exhibit antispasmodic activity. 
ER  -

