
TY  - JOUR
A1  - Hancox, NC 
T1  - The reaction between acetone and ammonia. III. Reduced pyridine, deriviaties
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1953
VL  - 6
IS  - 2
SP  - 143
EP  - 151
KW  - 
UR  - https://doi.org/10.1071/CH9530143 
N2  - The preparation of 2,2,4,6-tetramethyldihydropyridine by the reaction of acetone and ammonia at temperatures of 100-180 °C. has been studied; using an alkaline catalyst at 120 °C. for 3 hr, a yield of over 60 per cent. can be obtained. This dihydro-pyridine is identical with the product obtained by Matter (1948) in the pyrolysis of 2,2,4,4,6-pentamethyltetrahydropyrimidine Possible mechanisms for its formation are discussed. Catalytic hydrogenation over Raney nickel leads to tetramethyl-piperidine, while with palladium a partial reduction product, formulated as 2,2,4,6-tetramethyl-2,3,4,5-tetrahydropyridine is obtained ; the chemistry of these reduction products has been examined. 
ER  -

