
TY  - JOUR
A1  - Sheldon, Roger A. 
A1  - Rantwijk, Fred van 
T1  - Biocatalysis for Sustainable Organic Synthesis
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2004
VL  - 57
IS  - 4
SP  - 281
EP  - 289
KW  - antibiotics&#8212;biotechnology&#8212;CLEAs&#8212;enzymes&#8212;industrial chemistry
UR  - https://doi.org/10.1071/CH03291 
N2  - Biocatalysis offers mild reaction conditions, an environmentally attractive catalyst&#8211;solvent system, high activities, and chemo-, regio-, and stereoselectivities, while the use of enzymes generally circumvents the need for functional group activation and avoids protection/deprotection steps required in traditional organic syntheses. This review, using &#946;-lactam antibiotics as an example, discusses recent advances in biocatalysis research towards the goal of &#8216;green&#8217; methodologies for the manufacture of (fine) chemicals and the emulation of a cell&#39;s enzymatic cascade processes. 
ER  -

