
TY  - JOUR
A1  - Faizi, S. 
A1  - Wasi, A. 
A1  - Siddiqui, B. S. 
A1  - Naz, A. 
T1  - New Terpenoids from the Roots of <emph type="2">Melia azedarach</emph>
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2002
VL  - 55
IS  - 4
SP  - 291
EP  - 296
KW  - 
UR  - https://doi.org/10.1071/CH01101 
N2  - Two new terpenoids, bakayanolide (1) and 2&#945;-hydroxy-3&#946;-methoxy-6-oxo-13&#945;,14&#946;,17&#945;-lanosta-7,24-dien-21,16&#946;-olide (2), together with the known compounds 6&#946;-hydroxy-3-oxo-13&#945;,14&#946;,17&#945;-lanosta-7,24-dien-21,16&#946;-olide (3), sendanolactone (4), kulactone (5), and &#946;-sitosterol have been isolated from the ethanolic root extracts of Melia azedarach. Triterpenoids (4), (5), and &#946;-sitosterol have been identified previously from M. azedarach, while it is the first instance of the isolation of (3) from this source. The identity of these compounds was established through extensive spectroscopic methods (infrared and mass spectroscopy, 1H and 13C nuclear magnetic resonance) as well as appropriate two-dimensional nuclear magnetic resonance experiments. Bakayanolide (1) belongs to the rare class of C11 odd terpenes. Compounds (3) and (4) possessed moderate cytotoxic activity against KB cell lines. 
ER  -

