
TY  - JOUR
A1  - Zhu, Ying 
A1  - Zhu, Qi Xiu 
A1  - Jia, Zhong Jian 
T1  - Epoxide Sesquiterpenes and Steroids from <emph type="2">Cremanthodium discoideum</emph>
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2001
VL  - 53
IS  - 10
SP  - 831
EP  - 834
KW  - Sesquiterpene; steroid; antibacterial; cytoxicity; Compositae; Cremanthodium discoideum.
UR  - https://doi.org/10.1071/CH00100 
N2  - Two new epoxide bisabolane sesquiterpenes and a new steroid were isolated from the whole plants of Cremanthodium discoideum Maxim. Their structures have been established by spectroscopic methods including two-dimensional n.m.r. (1H&#8211;1H COSY, 1H&#8211;1H NOESY, HMBC, HMQC) techniques. Six known steroids were also isolated and characterized. Compound (1) has antibacterial activity against Bacillus aeruginosus and B. subtilis. Two sesquiterpenes showed significant activity against two tumour cell lines: human promyelocytic leukemia cell HL-60 and human hapatoma cell SMMC-7721. 
ER  -

