
TY  - JOUR
A1  - Bagnell, Laurence 
A1  - Bliese, Marianne 
A1  - Cablewski, Teresa 
A1  - Strauss, Christopher R. 
A1  - Tsanaktsidis, John 
T1  - Environmentally Benign Procedures for the Preparation and Isolation of 3-Methylcyclopent-2-en-1-one
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1997
VL  - 50
IS  - 9
SP  - 921
EP  - 926
KW  - 
UR  - https://doi.org/10.1071/C97097 
N2  - A moderately yielding (50&#177;4%) method for obtaining 3-methylcyclopent-2-en-1-one from hexane-2,5-dione in &#x2265;99&#183;5% purity was developed, using 2&#183;1% (w/v) of aqueous KOH at reflux. However, the yield was increased to 80&#177;5% by using considerably lower concentrations of base (&#60;0&#183;1%) and higher temperature (200&#176;C) with a conventionally heated autoclave or a microwave batch reactor. The preparation was scaled up with a larger autoclave and also with a continuous flow microwave reactor. The dione impurity was removed from the enone by preferential adsorption on an anion-exchange resin in the bisulfite form. The product was recovered from the aqueous phase with a hydrophobic resin. This environmentally benign, non-extractive isolation method has potential for broad applicability in cleaner production. 
ER  -

