
%0 Journal Article
%A Prager, Rolf H. 
%A Schafer, Karl 
%T Potential GABA<emph tye="8">B</emph> Receptor Antagonists. X The Synthesis of Further Analogues of Baclofen, Phaclofen and Saclofen
%J Australian Journal of Chemistry
%D 1997/10/14
%V 50
%N 8
%P 813-824
%K 
%R https://doi.org/10.1071/C97031
%U https://www.publish.csiro.au/paper/C97031 
%X In an attempt to obtain new compounds with binding activity at the GABAB receptor site, we report the synthesis of 3-amino-2-arylpropanoic acids, and the sulfonic, phosphonic and hydroxamic acid analogues. In addition, we report the synthesis of the isomer of phaclofen, 3-amino-1-(4-chlorophenyl)-propylphosphonic acid, and the higher homologue of baclofen, 5-amino-2-(4-chlorophenyl)pentanoic acid. 
