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Chemical Modification of Cellulose Membranes for SPOT Synthesis

Wenyi Li https://orcid.org/0000-0003-3584-0301 A D , John D. Wade https://orcid.org/0000-0002-1352-6568 B C , Eric Reynolds https://orcid.org/0000-0002-6618-4856 A and Neil M. O’Brien-Simpson https://orcid.org/0000-0001-8462-5603 A D
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A Bio21 Institute and Melbourne Dental School, University of Melbourne, Melbourne, Vic. 3010, Australia.

B Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic. 3010, Australia.

C School of Chemistry, University of Melbourne, Melbourne, Vic. 3010, Australia.

D Corresponding authors. Email: wenyi.li@unimelb.edu.au; neil.obs@unimelb.edu.au




Wenyi Li received his doctoral degree in 2016 from the University of Melbourne under the supervision of Professors John D. Wade and Frances Separovic. His doctoral thesis on antimicrobial peptide development was awarded the Graham Johnston Best Thesis Award by the RACI. From 2016 to 2018, he was based at the Leibniz-Institute of Molecular Pharmacology, Germany, where he was partially supported as a Leibniz-DAAD postdoctoral fellow, conducting research into protein semisynthesis and chemical ligation. In November 2018, he moved back to the University of Melbourne to work on further development of antibacterial polymers and peptides in the groups of Professors Neil M. O’Brien-Simpson and Greg Qiao.



John D. Wade obtained his Ph.D. degree on the structural basis of the diabetogenic action of growth hormones in 1979 from Monash University, Australia. He received a Nuffield Foundation Fellowship to Cambridge, UK, to undertake post-doctoral studies on the development of the Fmoc-solid phase peptide synthesis methodology in the laboratory of Dr R. C. Sheppard at the MRC Laboratory of Molecular Biology. In 1983, he returned to Melbourne at the invitation of the now Florey Institute of Neuroscience and Mental Health, University of Melbourne, where he heads the Laboratory of Peptide and Protein Chemistry. His interests are in solid phase peptide synthesis of large, complex, functionalized and often multi-chain peptides. Professor Wade is an NHMRC of Australia Principal Research Fellow and a Fellow of both the Royal Australian Chemical Institute and the Royal Society of Chemistry.



Laureate Professor Eric Reynolds AO PhD FICD FTSE FRACDS is Chief Executive Officer and Research Director of the Oral Health CRC at the Melbourne Dental School in The University of Melbourne. Eric was Head of the Melbourne Dental School for 16 years until 2015. He has lectured and published extensively and has chaired and participated in a wide range of professional committees and panels.



Neil M. O’Brien-Simpson graduated from Edinburgh Napier University in 1992 with a B.Sc. with honours in science and management studies. He moved to Australia and completed a Ph.D. in peptide-polymer vaccines in 1998 at The University of Melbourne. He is currently a professor and his research interests include antimicrobial peptides/materials, nanoparticles for peptide and vaccine delivery and bacterial outer membrane vesicles-host interactions. He has several editorial duties and is the current president of the Peptide Users Group of the Royal Australian Chemical Institute.

Australian Journal of Chemistry 73(3) 78-84 https://doi.org/10.1071/CH19335
Submitted: 19 July 2019  Accepted: 17 August 2019   Published: 12 September 2019



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